Depression Clinical Trials in Miami: What to Know Before You Join

Many people with depression improve with therapy and medication, but a significant number keep struggling after trying several treatments. For some of them, a clinical trial can be a way to access new options while helping advance care for others. Here is what to know before you decide.

Who May Qualify for a Depression Study?

Each study has its own criteria. Many depression trials enroll adults with a current episode of major depression, and some look specifically for people who still have symptoms while taking an antidepressant. Your age, other health conditions and current medications are also reviewed during screening.

What Study Visits Look Like

• A screening visit with questionnaires, a medical review and, sometimes, lab tests.
• Regular visits to check your mood, side effects and overall health.
• Clear instructions about the study medication and how to reach the team at any time.
• A final follow-up visit when your participation ends.

Questions to Ask Before You Join

• What is the goal of the study and how long does it last?
• Is there a placebo, and can I keep my current treatment?
• What are the possible risks and side effects?
• What happens if I want to stop?

Our Experience in Depression Research

Dr. Alen Hidalgo has participated as an investigator in depression trials, including Phase 3 studies of new add-on treatments for major depressive disorder. Learn more on our depression clinical trials page or read about treatment-resistant depression.

Frequently Asked Questions

Can I join a study if I am already taking an antidepressant?

Often, yes. Some studies are specifically designed for people who are taking an antidepressant but still have symptoms. The coordinator will review your medications with you.

Will I stop my current treatment?

Never without medical guidance. Any change to your medications is discussed with you in advance and is always supervised by the medical team.

What if my symptoms get worse during the study?

You will have direct contact with the study team, and your safety always comes first. If you are ever in crisis, call or text 988 or call 911.

Interested in a depression study? Contact our research team at Hidalgo Clinical Research Institute in Miami.